发明名称 NEUROMUSCULAR BLOCKING AGENTS
摘要 FIELD: medicine. SUBSTANCE: product: physiologically acceptable 1R-cis, 1'R-cis-2,2'-(3,11-dioxo-4,10-dioxatridecylene)-bis- -1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl isoquinoline salt free of other geometric and optical isomers, and composition stimulating nervous-muscle blockade based on thereof. 1R-cis, 1'R-cis-isomer shows preferable combination of pharmacological properties and less harmful effect on autonomic nervous system as compared with the known mixture of geometric and optical isomers. EFFECT: improved property, enhanced effectiveness. 11 cl, 1 tbl
申请公布号 AU8190491(A) 申请公布日期 1992.02.04
申请号 AU19910081904 申请日期 1991.07.12
申请人 THE WELLCOME FOUNDATION LIMITED 发明人 DEREK ANTHONY HILL;GEOFFREY LLOYD TURNER
分类号 A61K31/47;A61K31/472;A61K31/4725;A61P21/02;C07B57/00;C07D217/16;C07D217/20 主分类号 A61K31/47
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