| 发明名称 |
Microbial transformation process for antihypertensive products |
| 摘要 |
Fermentation of the microorganism Streptomyces sp. MA6751 (ATCC No. 55043) in the presence of the Angiotensin II (A II) receptor antagonist <IMAGE> (II) yields an N2-tetrazole beta -glucuronide analog which is also an A II antagonist useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
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| 申请公布号 |
US5085992(A) |
申请公布日期 |
1992.02.04 |
| 申请号 |
US19910659641 |
申请日期 |
1991.02.25 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHEN, SHIEH-SHUNG T.;DOSS, GEORGE |
| 分类号 |
C07D471/04;C07H19/056;C12P19/26 |
主分类号 |
C07D471/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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