发明名称 AMIDOBENZENES
摘要 AMIDOBENZENES The invention concerns novel phenoxy- and phenylthio-acetyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.
申请公布号 CA2048318(A1) 申请公布日期 1992.02.03
申请号 CA19912048318 申请日期 1991.08.01
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 BRITTAIN, DAVID R.;BROWN, STEVEN P.;COOPER, ANTHONY L.;LONGRIDGE, JETHRO L.;MORRIS, JEFFREY J.;PRESTON, JOHN;SLATER, LINDA
分类号 A61K31/255;A61P3/08;A61P43/00;C07C313/04;C07C317/40;C07C323/41;C07C323/60;(IPC1-7):C07C317/50;A61K31/165;C07C323/65 主分类号 A61K31/255
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