发明名称 |
DNA coding for a human vasoconstrictive peptide and use thereof. |
摘要 |
<p>Disclosed are (1) a DNA containing a cDNA segment coding for human endothelin-2 (SEQ ID NO:1), (2) a precursor of human endothelin-2 (SEQ ID NO:2), (3) a transformant carrying a DNA containing a cDNA segment coding for human endothelin-2, and (4) a method for preparing mature human endothelin-2 which comprises culturing the transformant described in (3), accumulating a protein in a culture medium, and collecting the same, whereby human endothelin-2 and the precursors thereof can be produced in large amounts.</p> |
申请公布号 |
EP0468337(A1) |
申请公布日期 |
1992.01.29 |
申请号 |
EP19910111815 |
申请日期 |
1991.07.16 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
ONDA, HARUO;OHKUBO, SHOICHI;KOSAKA, TAKUO |
分类号 |
A61K38/00;C07K14/00;C07K14/575;C12N1/21;C12N15/09;C12N15/12;C12N15/16;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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