Pyrimidine derivatives.

摘要

A pyrimidine derivative has the formula, <CHEM> wherein each of R<1> and R<2>, which may be the same or different, is C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkoxy or halogen; R<3> is hydrogen or C1-C6 alkyl; R<4> is C1-C6 alkyl, halo C1-C6 alkyl, benzyl, phenyl or phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl, nitro and halogen; X is oxygen or sulfur; Z is nitrogen or CY<4>; each of Y<1>, Y<2> and Y<3>, which may be the same or different, is hydrogen, halogen, C1-C6 alkyl or C1-C6 alkoxy; and Y<4> is hydrogen, hydroxyl, mercapto, nitro, halogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C3-C6 alkenyloxy, C3-C6 alkynyloxy, halo C1-C6 alkyl, halo C2-C6 alkenyl, halo C2-C6 alkynyl, halo C1-C6 alkoxy, halo C3-C6 alkenyloxy, halo C3-C6 alkynyloxy, C1-C6 alkoxy C1-C6 alkyl, C3-C6 alkenyloxy C1-C6 alkyl, C3-C6 alkynyloxy C1-C6 alkyl, cyano, formyl, carboxyl, C1-C6 alkoxycarbonyl, C3-C6 alkenyloxycarbonyl, C3-C6 alkynyloxycarbonyl, phenyl, phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenoxy, phenoxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenylthio, phenylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, benzyloxy, benzyloxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, benzylthio, benzylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, <CHEM> wherein each of R<5> and R<6>, which may be the same or different, is hydrogen, C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl, <CHEM> wherein R<5> and R<6> are as defined above, <CHEM> wherein R<7> is C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl and m is an integer of 0, 1 or 2, <CHEM> wherein X<1> is oxygen or sulfur, and R<7> is as defined above, or <CHEM> wherein R<7> and m are as defined above, and n is an integer from 1 to 4.