发明名称 COMBINATION THERAPY USING ANTI-EGFR ANTIBODIES AND ANTI-HORMONAL AGENTS
摘要 The invention relates to a combination therapy for the treatment of tumors a nd tumor metastases, preferably breast and prostate tumors, comprising administration of anti-EGFR (Her1) antibodies and anti-hormonal agents, optionally together with cytotoxic / chemotherapeutic agent. The method and the pharmaceutical compositions comprising said agents can result in a synergistic potentiation of the tumor cell proliferation inhibition effect o f each individual therapeutic agent, yielding more effective treatment than found by administering an individual component alone.
申请公布号 CA2449166(A1) 申请公布日期 2002.11.14
申请号 CA20022449166 申请日期 2002.04.22
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 HARSTRICK, ANDREAS;ROSEN, OLIVER
分类号 A61K45/00;A61K31/00;A61K31/565;A61K38/00;A61K39/395;A61P35/00;A61P35/04;A61P43/00;C07K16/28;C07K16/46;(IPC1-7):A61K39/395 主分类号 A61K45/00
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