REPRODUCTIVE CANCER DIAGNOSIS AND THERAPY

摘要

A method of detecting a cancer cell or tissue of the reproductive system suc h as prostate cancer, breast cancer, ovarian cancer, cervical cancer and uteri ne cancer uses detection of relatively increased levels of ghrelin, an exon 3- deleted form of preproghrelin and/or growth hormone secretagogue type 1b receptor expression by cancer cells as compared to normal cells and tissues of the reproductive system. Also provided is an exon 3-deleted form of preproghrelin and antibodies thereto as well interventionist strategies that target ghrelin and/or growth hormone secretagogue receptors in treating cancers of the reproductive system such as prostate cancer and breast cancer , although without limitation thereto.