| 摘要 |
NEW MATERIAL:The compound of formula (R1 is H, OH or acetyloxy; R2 and R5 are OH or acetyloxy; R3 and R7 are methyl; R4, R6 and R8 are H or OH; R3 and R4 may together form terminal methylene; R7 and R8 may together form terminal methylene; R5 and R6 may together form epoxy; R5 may together with 27-carbon atom form pyran ring; R5 may together with 25-carbon atom form furan ring). EXAMPLE:3-0-acetyl-2,20,22,25-tetradeoxy-22,23-epoxy-24-hydroxymakiste rone A. USE:Carcinostatic agent. PREPARATION:The objective compound is produced by extracting CHOREI (dried sclerotium of Polyporus umbellatus belonging to family Polyporaceae) with a water-soluble solvent (e.g. water and methanol) and fractionating and purifying the extract by chromatography. |
