DNA CODING FOR HUMAN FK506-BINDING PROTEIN AND EXPRESSION THEREOF

摘要

A DNA containing a base sequence which codes for a human FK506-binding protein composed of 108 amino acid residues; a recombinant human FK506-binding protein prepared by the expression of the DNA; and an expression vector for use in the expression and a transformant. The invention serves to establish a process for mass-producing a human FK506-binding protein and realizes a stabilized supply of a human FK506-binding protein having a peptidylprolyl cis-trans isomerase activity for screening immunosuppressants.