发明名称 |
PHARMACEUTICAL COMPOSITION FOR RAPID SUSPENSION IN WATER |
摘要 |
The invention provides a solid pharmaceutical composition for addition to water to produce a suspension of a drug comprising (a) a drug which is substantially water-insoluble or microencapsulated; (b) a thickening or suspending agent; (c) a pharmaceutically acceptable acid; (d) a pharmaceutically acceptable carbonate or bicarbonate; characterised in that the weight ratio of c + d:b is from 1:1.5 to 1:15 and the amount of c + d is sufficient to obtain rapid hydration of the thickening or suspending agent (b) when the composition is mixed with water such that a homogeneous suspension of the drug is obtained within 30 seconds. A method for preparing the composition is also described. |
申请公布号 |
WO9200731(A1) |
申请公布日期 |
1992.01.23 |
申请号 |
WO1991EP01268 |
申请日期 |
1991.07.04 |
申请人 |
EURAND INTERNATIONAL SPA |
发明人 |
ZEMA, MARCO;MAPELLI, LUIGI, GIOVANNI;MARCONI, MARCO, GIUSEPPE, RAFFAELE |
分类号 |
A61K9/00;A61K9/10;A61K9/107;A61K9/46;A61K9/50 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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