发明名称 N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them.
摘要 <p>A compound of the formula &lt;CHEM&gt; wherein: X&lt;1&gt; is halo; X&lt;2&gt; is hydrogen, halo, or CF3; A is C2-C7 alkyl; C2-C7 alkenyl; C4-C8 cycloalkyl; phenyl-substituted C1-C4 alkyl; phenyl-substituted C2-C4 alkenyl; or RZR&lt;1&gt; where R is phenyl or C1-C3 alkyl, R&lt;1&gt; is (CH2)n where n is 1-3, and Z is oxygen or sulfur; and pharmaceutically acceptable salts thereof, for the manufacture of a medicament for the treatment of susceptible neoplasms.</p>
申请公布号 EP0467621(A1) 申请公布日期 1992.01.22
申请号 EP19910306391 申请日期 1991.07.15
申请人 ELI LILLY AND COMPANY 发明人 CROWELL, THOMAS ALAN;HOWBERT, JAMES JEFFRY;WARD, JOHN STANLEY
分类号 A61K31/18;A61K31/64;A61P35/00;C07C311/55;C07C311/56;C07C323/67 主分类号 A61K31/18
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