发明名称 |
N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them. |
摘要 |
<p>A compound of the formula <CHEM> wherein: X<1> is halo; X<2> is hydrogen, halo, or CF3; A is C2-C7 alkyl; C2-C7 alkenyl; C4-C8 cycloalkyl; phenyl-substituted C1-C4 alkyl; phenyl-substituted C2-C4 alkenyl; or RZR<1> where R is phenyl or C1-C3 alkyl, R<1> is (CH2)n where n is 1-3, and Z is oxygen or sulfur; and pharmaceutically acceptable salts thereof, for the manufacture of a medicament for the treatment of susceptible neoplasms.</p> |
申请公布号 |
EP0467621(A1) |
申请公布日期 |
1992.01.22 |
申请号 |
EP19910306391 |
申请日期 |
1991.07.15 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
CROWELL, THOMAS ALAN;HOWBERT, JAMES JEFFRY;WARD, JOHN STANLEY |
分类号 |
A61K31/18;A61K31/64;A61P35/00;C07C311/55;C07C311/56;C07C323/67 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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