4-Substituted-2-hydroxybutanoates and a process for producing them.

摘要

The present invention provides an optically active 4-substituted-2-hydroxybutanoate represented by the general formula: <CHEM> wherein X is Cl, Br, I or CN, R is alkyl, and * shows an asymmetric carbon. The compound which is useful chemical compounds as starting materials of medical supplies, is obtained by a process comprising ring-opening optically active alpha -hydroxy- gamma -butyrolactone and esterifying the compound obtained.