摘要 |
<p>A trehalose derivative of the formula: <CHEM> wherein one, two, three or four of R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7> and R<8> are independently selected from the group consisting of C1-40 aliphatic acyl groups and all the rest of them are hydrogen atoms, with the proviso that: a) when one of them is C1-40 aliphatic acyl group, then it is not 2-palmitoyl or 6-aliphatic acyl, b) when two of them are C1-40 aliphatic acyl groups, then they are not located at corresponding positions with each other, c) when three of them are C1-40 aliphatic acyl groups, then they are not 2,3,2 min -tripalmitoyl, and d) when four of them are C1-40 aliphatic acyl groups, then they are not located at corresponding positions with each other or at 2,3,4,2 min - or 2,3,6,2 min -positions. The compounds of the above formula have anti-tumor activity.</p> |
申请人 |
SAWAI PHARMACEUTICAL CO., LTD. |
发明人 |
YOSHINAGA, JUNJI;SHOGAKI, TAKESHI;KAKITA, TAKOA;OZEKI, HIROMI;KATO, YOSHIKO |