| 摘要 |
Biodegradable absorption enhancers, especially useful in pharmaceutical formulations, are compounds having the formula <IMAGE> (I) wherein R is hydrogen, C1-C7 alkyl, benzyl or 4-hydroxybenzyl; n is a whole number from 4 to 18 inclusive; R1 and R2 are independently selected from hydrogen and C1-C7 alkyl, or R1 and R2 together with the nitrogen atom to which they are attached are combined to form a substituted or unsubstituted heterocycloalkyl radical having a total of 5 to 7 ring atoms, optionally including a hetero ring atom selected from oxygen, sulfur and nitrogen in addition to the indicated nitrogen atom, the substituents when present being one to three C1-C7 alkyl radicals, which may be the same or different; and R3 and R4 are independently selected from hydrogen, methyl and ethyl.
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