发明名称 |
COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS |
摘要 |
A photoactivatible nucleoside analogue is disclosed, comprising a coumarin moiety linked through its phenyl ring to the 1-position of a ribose or deoxyribose sugar moiety. The resulting nucleoside analogue is typically used as a photocrosslinking group when inserted into a polynucleotide as a replacement for one or more of the complementary nucleoside bases present in a probe used in a hybridization assay.
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申请公布号 |
US5082934(A) |
申请公布日期 |
1992.01.21 |
申请号 |
US19890333632 |
申请日期 |
1989.04.05 |
申请人 |
NAXCOR |
发明人 |
SABA, DON;GLASS, RICHARD S.;YABUSAKI, KENICHI K. |
分类号 |
C07H15/26;C07H17/075;C07H21/00;C07H21/04 |
主分类号 |
C07H15/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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