The present invention relates to Fc variants having decreased affinity for FcgammaRI, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
申请公布号
US2007286859(A1)
申请公布日期
2007.12.13
申请号
US20070766581
申请日期
2007.06.21
申请人
XENCOR, INC.
发明人
LAZAR GREGORY A.;DANG WEI;DESJARLAIS JOHN R.;KARKI SHER B.;VAFA OMID;HAYES ROBERT
