| 发明名称 |
SELECTION OF RIBOZYMES THAT EFFICIENTLY CLEAVE TARGET RNA |
| 摘要 |
(57) Using the method herein ribozymes are screened by culturing cells whose survival is dependent upon cleavage of RNA by a ribozyme within the cell. Cleavage by the ribozyme allows the cells to survive. The surviving cells are selected and contain the most effective ribozymes.
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| 申请公布号 |
CA2087519(A1) |
申请公布日期 |
1992.01.17 |
| 申请号 |
CA19912087519 |
申请日期 |
1991.07.16 |
| 申请人 |
NEW YORK HEALTH RES INST |
发明人 |
KRAMER FRED RUSSELL;DRLICA KARL A;PINTER ABRAHAM;DUBNAU DAVID |
| 分类号 |
C12N9/10;C12N15/10;C12N15/113;C12Q1/68;(IPC1-7):C12N15/64;C12N15/01;C12Q1/02;C07H21/04;C12N15/49;C12N15/55;C12Q1/70 |
主分类号 |
C12N9/10 |
| 代理机构 |
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代理人 |
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