发明名称 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND.
摘要 <p>A process for producing a diphenyl sulfone compound of general formula (I) by the reaction of a 4,4'-dihydroxydiphenyl sulfone with a compound R-X (wherein R represents C1 and C8 alkyl, C3 to C8 cycloalkyl, C2 to C8 alkenyl, or arylalkyl which may be substituted on the aromatic ring, and X represents halogen).In the formula, R is as defined above. The process is characterized by conducting the reaction in the presence of 1.5 to 3 mol of an alkali per mole of the starting sulfone in 0.3 to 1.5 parts by weight of water as the solvent per part by weight of the sulfone. This process is industrially advantageous in that 4-(substituted hydroxy)-4'-hydroxydiphenyl sulfones, especially 4-n-propoxy-4'-hydroxydiphenyl sulfone or 4-isopropoxy-4'-hydroxydiphenyl sulfone, can be produced selectively and economically with the use of an inexpensive solvent.</p>
申请公布号 EP0465665(A1) 申请公布日期 1992.01.15
申请号 EP19910902774 申请日期 1991.01.28
申请人 YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. 发明人 KINISHI, RYOICHI;OZAKI, YOSHIHIRO
分类号 C07C315/00;C07C315/04;C07C317/22 主分类号 C07C315/00
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