发明名称 NOVEL HETEROCYCLIC DICARBOXYLIC ACIDS
摘要 A compound selected from the group consisting of a compound of the formula <IMAGE> I wherein the dotted lines represent a possible endo or exo double bond, R1 and R2 are individually selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms, aryl of 6 to 14 carbon atoms, aralkyl of 7 to 18 carbon atoms and <IMAGE> R'2 is alkyl of 1 to 8 carbon atoms or aryl of 6 to 14 carbon atoms, X is -O- or -NR-, R is selected from the group consisting of hydrogen <IMAGE> and -COOR', R' is hydrogen or alkyl of 1 to 8 carbon atoms, Y is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and alkenyl and alkynyl of 2 to 8 carbon atoms, all optionally substituted with at least one halogen or -OH, with the proviso that if Y is -OH, X is not -NH- and their non-toxic, pharmaceutically acceptable addition salts of acids or bases having antibacterial and immunological properties.
申请公布号 US5081135(A) 申请公布日期 1992.01.14
申请号 US19900580213 申请日期 1990.09.10
申请人 ROUSSEL UCLAF 发明人 AGOURIDAS, CONSTANTIN;FAUVEAU, PATRICK
分类号 A61K31/35;A61K31/351;A61K31/445;A61K39/39;A61P31/04;A61P35/00;A61P37/00;A61P43/00;C07D211/18;C07D211/60;C07D211/78;C07D309/08;C07D309/10;C07D309/28 主分类号 A61K31/35
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