TETRAOXODIAZABICYCLO-(3,3,1)-NONANE.

摘要

Cpds. (I) and their acid addn. salts are new. In (I) R1 and R2 are alkyl, alkenyl or alkynyl; and R2 and R4 are each alkyl or together represent alkylene; with the proviso that R1-R4 together contain at least 5 C-atoms. (I) has an oxygen-sparing action, influence the heart rate, and have an antiarrhythmic action. The cpds. have good physiological tolerance, in particular having only an extremely slight negative effect on cardiac contractile force. (I) show a positive inotropic effect at low dosages.