| 摘要 |
<p>Human insulin analogues wherein at least one of the amino acid residues in position B1-B6 has been replaced by a Lys or Arg have a prolonged insulin action. Asn in position A21 may be replaced by another amino acid residue to increase the stability of the insulin analogue in acid solution. Furthermore B30 may be blocked by means of an amido or ester group.</p> |
