摘要 |
PURPOSE:To industrially obtain L-lysine with reduced cooling load without requiring an amino acid by culturing a variant belonging to the genus Corynebacterium in a medium. CONSTITUTION:A variant [preferably Corynebacterium thermoaminogenes AJ 12,521 (FERM P-11,409), Corynebacterium thermoaminogenes AJ 12,522 (FERM P-11,410), Corynebacterium thermoaminogenes AJ 12,533 (FERM P-11,411), or Corynebacterium thermoaminogenes AJ 12,524 (FERM P-11,412)] belonging to the genus Corynebacterium, capable of growing at >=40 deg.C, having resistance to S-(2-aminoethyl)-L-cysteine and producing L-lysine is subjected to shaking culture or aerated spinner culture in a medium preferably at 35-45 deg.C for 2-4 days to give L-lysine. |