| 摘要 |
The invention relates to a method of selecting an active agent for modifying the shape of keratin fibres, comprising the following steps: a) culturing mammalian cells, b) adding the test substance to the mammalian cell culture, c) after incubation, assaying the amount of glycosaminoglycans (GAGs) in the mammalian cells or in the mammalian cell culture medium, d) comparing the amount of GAGs measured in step c with that measured starting from a control culture of mammalian cells, obtained under the same conditions, but in the absence of test substance, e) selecting the substances for which the amount of GAGs is modified by at least a factor of 0.5 relative to the amount measured in the control culture. It also relates to the cosmetic use of an active agent thus selected, as an agent for modifying the shape of keratin fibres, and to a cosmetic process involving this agent. |
