Enzymatic, enantioselective preparation of R-glycidol.

摘要

Enzymatic, enantioselective preparation of R-glycidol by subjecting a mixture of R,S-glycidol to the effect of a suitable enantioselective oxidizing enzyme. Suitable enzymes are alcohol dehydrogenases, in particular PQQ dependent alcohol dehydrogenases. In this manner R-glycidol with a high e.e. can be prepared with relatively low conversion.