发明名称 COMPOSITION FOR THE TOPICAL TREATMENT OF GLAUCOMA OR OCULAR HYPERTENSION
摘要 PCT No. PCT/SE88/00129 Sec. 371 Date Nov. 22, 1988 Sec. 102(e) Date Nov. 22, 1988 PCT Filed Mar. 15, 1988 PCT Pub. No. WO88/07380 PCT Pub. Date Oct. 6, 1988.A method for the topical treatment of glaucoma or ocular hypertension which comprises contacting the surface of the eye with a composition consisting essentially of an effective intraocular pressure reducing amount of a mixture of (a) an adrenergic agonist selected from the group consisting of epinephrine, dipivalylepinephrine, norepinephrine, phenylephrine, clonidine, isoproterenol, salbutamol, metaproterenol and terbutaline, and (b) a phosphodiesterase inhibitor selected from the group consisting of isobutylmethylxanthine, theophyllamine, Rolipram and RO-2017624, in an ophthalmically compatible carrier.
申请公布号 US5079253(A) 申请公布日期 1992.01.07
申请号 US19880278533 申请日期 1988.11.22
申请人 PHARMACIA AB 发明人 HOYNG, PHILIP;STJERNSCHANTZ, JOHAN W.
分类号 A61K9/00;A61K31/135;A61K31/52;A61K45/06;A61P27/02 主分类号 A61K9/00
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