发明名称 ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES
摘要 Ether lipid nucleoside covalent conjugates and derivatives thereof are disclosed, along with pharmaceutical compositions containing the same and methods of using the same to combat HIV-1 infections. Illustrative are 3'-Azido-3'-deoxythymidine-5'-monophosphate-D,L-3 octadecanamido-2-ethoxypropane and 3'-Azido-3'-deoxythymidine-5' butyrate- gamma -N,N,N-trimethyl-ammonium- beta -(1-phospho-2-ethoxy-3-hexadecyloxypropane).
申请公布号 AU8059791(A) 申请公布日期 1992.01.07
申请号 AU19910080597 申请日期 1991.06.14
申请人 WAKE FOREST UNIVERSITY 发明人 CLAUDE PIANTADOSI;CANIO J. MARASCO JR.;LOUIS S. KUCERA
分类号 A61K31/715;A61P31/12;C07F9/09;C07F9/10;C07H19/10;C07H19/20;C07H19/207 主分类号 A61K31/715
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