alpha -1-antichymotrypsin, analogues and methods of production

摘要

The invention provides alpha -1-antichymotrypsin and protein preparations comprising human alpha -1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human alpha -1-antichymotrypsin. The invention also provides methods for producing alpha -1-antichymotrypsin. The invention further provides analogues of alpha -1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.