Strong base reagent

摘要

alpha -Arylalkanoic acids are prepared by a method comprising the step of reacting an alkylaromatic compound corresponding to the desired alpha -arylalkanoic acid with a new metallation reagent solution. The reagent comprises the reaction product of alkyllithium or aryllithium and about two to five molar equivalents of potassium tert-alkoxide in a trialkylamine solvent.