发明名称 |
1-(2-(HYDROXYMETHYL)CYCLOALKYLMETHYL)-5-SUBSTITUTED URACILS |
摘要 |
TITLE OF INVENTION 1-¢2-(HYDROXYMETHYL)CYCLOALKYLMETHYL!-5-SUB-STITUTED URACILS 1-¢2-(Hydroxymethyl)cycloalkylmethyl!-5-substituted uracils which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation. |
申请公布号 |
CA1293972(C) |
申请公布日期 |
1992.01.07 |
申请号 |
CA19880566441 |
申请日期 |
1988.05.10 |
申请人 |
MERCK & CO., INC. |
发明人 |
TOLMAN, RICHARD L.;ASHTON, WALLACE T. |
分类号 |
A61K31/505;A61P31/12;A61P31/22;C07D239/54;C07D239/553 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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