发明名称 1-(2-(HYDROXYMETHYL)CYCLOALKYLMETHYL)-5-SUBSTITUTED URACILS
摘要 TITLE OF INVENTION 1-¢2-(HYDROXYMETHYL)CYCLOALKYLMETHYL!-5-SUB-STITUTED URACILS 1-¢2-(Hydroxymethyl)cycloalkylmethyl!-5-substituted uracils which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation.
申请公布号 CA1293972(C) 申请公布日期 1992.01.07
申请号 CA19880566441 申请日期 1988.05.10
申请人 MERCK & CO., INC. 发明人 TOLMAN, RICHARD L.;ASHTON, WALLACE T.
分类号 A61K31/505;A61P31/12;A61P31/22;C07D239/54;C07D239/553 主分类号 A61K31/505
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