Non-A, non-B hepatitis virus particles.

摘要

Disclosed are an isolated non-A, non-B hepatitis virus particle comprising at least one antigen selected from the group consisting of a core antigen, a matrix antigen and an envelope antigen of the non-A, non-B hepatitis virus and a method for efficiently producing the same by genetic engineering. The non-A, non-B hepatitis virus particle can advantageously be used not only for the production of an NANBV hepatitis vaccine exhibiting an extremely high immunogenicity and a diagnostic agent which is extremely high in the antibody detection ratio and in the degree of accuracy of the detection, but is also useful for researches on liver diseases, such as liver cancer.