发明名称 Preparation of fatty product microspheres loaded or not with an active substance.
摘要 <p>New process for the preparation of water-insoluble fatty product microspheres, loaded or not loaded with an active substance. This new process is characterised by the dissolution of at least one fatty product chosen from aliphatic alcohols having from 8 to 16 carbon atoms, aliphatic acids having from 8 to 15 carbon atoms and the esters of these or mixtures thereof, optionally with an active substance, in a water-miscible solvent which can also solubilise the aforementioned active substance, followed by the introduction of this mixture, preferably by injection using a syringe, into an aqueous medium with stirring and at a temperature between 4 DEG C and the melting point of the chosen fatty product(s) and by the recovery and drying of the microspheres thereby obtained. Use of the microspheres obtained according to the process in compositions for therapeutic or cosmetic application.</p>
申请公布号 EP0463962(A1) 申请公布日期 1992.01.02
申请号 EP19910401723 申请日期 1991.06.26
申请人 CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA 发明人 ROLLAND, ALAIN
分类号 A61K8/30;A61K8/04;A61K8/11;A61K8/34;A61K8/36;A61K8/37;A61K8/38;A61K8/49;A61K8/67;A61K9/16;A61K9/50;A61K47/10;A61K47/12;A61K47/14;A61Q19/00;B01J13/02 主分类号 A61K8/30
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