4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDYLPHENYLALKANE DERIVATIVES AS ANTIHISTAMINES AND METHODS OF TREATMENT OF AN ALLERGIC RESPONSE

摘要

4-(Hydroxydiphenylmethyl)-1-piperidylphenylalkane derivatives as antihistamines of the formula <IMAGE> and pharmaceutically acceptable salts of such derivatives are disclosed in which n is an integer between 0 and 2, R1-R5 represent, independently of one another, hydrogen and at least one of them represents a linear or branched alkyl radical with 1-4 carbon atoms, a C1-C3-alkoxy radical or a hydroxyl radical. A method of treatment of allergic response in mammals is also disclosed.