发明名称 |
Rationelt designede enkeltkædede meganukleaser med ikke-palindromiske genkendelsessekvenser |
摘要 |
Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition sequence half-sites are joined into a single polypeptide to form a functional heterodimer with a non- palindromic recognition sequence. The invention also relates to methods of producing such meganucleases, and methods of producing recombinant nucleic acids and organisms using such meganucleases. |
申请公布号 |
DK2660317(T3) |
申请公布日期 |
2016.08.01 |
申请号 |
DK20130165733T |
申请日期 |
2008.10.31 |
申请人 |
Precision Biosciences, Inc. |
发明人 |
SMITH, James, Jefferson;JANTZ, Derek |
分类号 |
C12N9/22 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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