| 摘要 |
2084873 9200132 PCTABS00010 A single filtration device (12) containing coated filter membranes (32, 38, 62, 68) and absolute pore filters (34, 36, 64, 66) is provided in which the membranes (32, 38, 62, 68) and absolute pore filters (34, 36, 64, 66) are present in two sections (30, 60) of the filter device. The filter device (12) will remove viruses, as modeled by type-C Xenotropic retrovirus, with an efficiency of at least 4.6 x 105; remove DNA from levels of 10 .mu.g/sample to levels below 10 picograms per 500 mg sample of monoclonal antibody; and will remove at least 97 % of some bacterial endotoxins.
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