| 发明名称 |
PEPTIDES HAVING ATRIAL NATRIURETIC FACTOR ACTIVITY |
| 摘要 |
9451P/5879A 18005 TITLE OF THE INVENTION PEPTIDES HAVING ATRIAL NATRIURETIC FACTOR ACTIVITY Atrial natriuretic factor analogs containing N-alkylated amino acids and showing enhanced potency and increased metabolic stability. These analogs have natriuretic, diuretic and vasorelaxant activity, making them suitable for treating congestive heart failure and renal hypertension.
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| 申请公布号 |
CA2045420(A1) |
申请公布日期 |
1991.12.27 |
| 申请号 |
CA19912045420 |
申请日期 |
1991.06.25 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
NUTT, RUTH F.;VEBER, DANIEL F.;BRADY, STEPHEN F.;WILLIAMS, THERESA M. |
| 分类号 |
A61K38/00;A61K38/22;A61P7/10;A61P9/00;A61P9/08;A61P9/12;C07K14/575;C07K14/58;(IPC1-7):C07K14/58 |
主分类号 |
A61K38/00 |
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