发明名称 DIALKOXY-PYRIDINYL-BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE
摘要 The novel compounds of formula (I) and physiologically acceptable salts thereof, wherein R<1> and R<2>, which are different, is each H, alkyl containing 1-4 carbon atoms or -C(O)-R<5>; wherein R<5> is alkyl containing 1-4 carbon atoms or alkoxy containing 1-4 carbon atoms and one of R<1>, or R<2> is always selected from the group -C(O)-R<5>; R<3> and R<4> are the same or different and selected from -CH3, -C2H5, (a), (b), and -CH2CH2OCH3 or R<3> and R<4> together with the adjacent oxygen atoms attached to the pyridine ring and the carbon atoms in the pyridine ring form a ring, wherein the part constituted by R<3> and R<4> is -CH2CH2CH2-, or -CH2-CH2- or -CH2-; as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient and use of the compounds in medicine.
申请公布号 WO9119712(A1) 申请公布日期 1991.12.26
申请号 WO1991SE00416 申请日期 1991.06.11
申请人 AKTIEBOLAGET ASTRA 发明人 BRAENDSTROEM, ARNE, ELOF;LINDBERG, PER, LENNART;SUNDEN, GUNNEL, ELISABETH
分类号 A61K31/44;A61K31/4427;A61P1/04;C07D213/69;C07D235/28;C07D401/12;C07D401/14;C07D405/14;C07D491/04;C07D491/056 主分类号 A61K31/44
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