摘要 |
The novel compounds of formula (I) and physiologically acceptable salts thereof, wherein R<1> and R<2>, which are different, is each H, alkyl containing 1-4 carbon atoms or -C(O)-R<5>; wherein R<5> is alkyl containing 1-4 carbon atoms or alkoxy containing 1-4 carbon atoms and one of R<1>, or R<2> is always selected from the group -C(O)-R<5>; R<3> and R<4> are the same or different and selected from -CH3, -C2H5, (a), (b), and -CH2CH2OCH3 or R<3> and R<4> together with the adjacent oxygen atoms attached to the pyridine ring and the carbon atoms in the pyridine ring form a ring, wherein the part constituted by R<3> and R<4> is -CH2CH2CH2-, or -CH2-CH2- or -CH2-; as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient and use of the compounds in medicine. |