发明名称 TRANSDERMAL ADMINISTRATION OF BUPRENORPHINE
摘要 <p>Method and laminated composite (10) for administering buprenorphine transdermally to treat pain. The composite comprises an impermeable backing layer (11) and a reservoir layer (12) containing buprenorphine a release liner lamina (13) and optionally a permeation enhancer combined with a pressure-sensitive adhesive with the amounts of buprenorphine and optional enhancer being sufficient to cause the buprenorphine to pass through the skin at a rate in excess of about 0.05 mcg/cm2/hr.</p>
申请公布号 WO1991019474(A1) 申请公布日期 1991.12.26
申请号 US1991004189 申请日期 1991.06.12
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