发明名称 |
PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL WHICH CONTAINS IGG, IGA AND IGM AND CAN BE ADMINISTERED INTRAVENOUSLY |
摘要 |
Process for the preparation of an immunoglobulin solution suitable for intravenous administration from a human blood protein fraction containing immunoglobulins IgG, IgA and IgM in partially concentrated from, with the process steps: addition of acetate buffer to the protein fraction, where appropriate removal of insoluble constituents by filtration, treatment with calcium phosphate and octanoic acid, centrifugation, removal of the supernatant and treatment thereof with an adsorbent, removal of the adsorbent and sterilization by filtration.
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申请公布号 |
US5075425(A) |
申请公布日期 |
1991.12.24 |
申请号 |
US19900561033 |
申请日期 |
1990.08.01 |
申请人 |
BIOTEST PHARMA GMBH |
发明人 |
KOTITSCHKE, RONALD;STEPHAN, WOLFGANG;MOELLER, WOLFGANG;PIECHACZEK, DETLEF;RUDNICK, DIETER |
分类号 |
A61K39/395;A61K38/00;C07K16/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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