发明名称 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS
摘要 Triiodinated isophthalamide derivatives, useful as X-ray contrast agents, having at least one amide group derived from the amino-alcohol, 3-(N-2-hydroxyethyl)amino-1,2-propanediol, which provides high water solubility and low mammalian toxicity, and methods of preparing them. Methods of preparing 3-(N-2-hydroxyethyl)amino-1,2-propanediol are provided.
申请公布号 US5075502(A) 申请公布日期 1991.12.24
申请号 US19890450693 申请日期 1989.12.13
申请人 MALLINCKRODT, INC. 发明人 KNELLER, MILLS T.;LIN, YOULIN;WHEATLEY, JAMES R.
分类号 A61K49/04;C07C237/42;C07C237/46;C07D207/26;C07D207/27;C07D207/273 主分类号 A61K49/04
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