发明名称 |
STABILIZED PLASMINOGEN ACTIVATOR PRECURSOR AND METHOD OF PRODUCING THE SAME |
摘要 |
A plasminogen activator precursor obtainable from a serum-free culture fluid of human kidney cells is stabilized by adding to its solution poly-C1-C5-alkylene glycols, polyethylene-polyoxypropylene copolymers, mandelic acid salts, triethanolamine, acid addition salts of acetylglycillysine methyl ester, guanidine salts, thiocyanic acid salts, alkali metal iodides or serine.
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申请公布号 |
US5075230(A) |
申请公布日期 |
1991.12.24 |
申请号 |
US19900512511 |
申请日期 |
1990.04.20 |
申请人 |
THE GREEN CROSS CORPORATION |
发明人 |
MORIMOTO, KAZUO;SAGANE, MOTOSHI;OHARA, KAZUHIRO;NARITA, SHUSAKU |
分类号 |
A61K31/465;A61K38/43;A61K38/46;A61K38/48;A61K47/02;A61K47/10;A61K47/12;A61K47/18;A61K47/20;A61K47/34;A61K47/42;A61P7/02;C12N9/72;C12N9/96 |
主分类号 |
A61K31/465 |
代理机构 |
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代理人 |
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地址 |
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