| 发明名称 |
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| 摘要 |
<p>PURPOSE:To make the easy and quick discrimination of the presence or absence of a progressive cancer by adding a monoclonal antibody to 1-methyl adenosine to a specimen and measuring the generated 1-methyl adenosine-monoclonal antibody complex. CONSTITUTION:An animal is immunized by using the 1-methyl adenosine and the spleen cells of the animal are sampled. The 1-methyl adenosine alone cannot be an immune source in this stage; therefore, a carrier protein such as bovine serum albumin is conjugated thereto and the conjugate is used as the immune body. The spleen cells of the resulted immune animal are fused with the myeloma cells to obtain a hybridoma. The 1-methyl adenosine is measured by using the monoclonal antibody produced from the resulted hybridoma, by which the presence or absence of the progressive cancer is easily and quickly discriminated.</p> |
| 申请公布号 |
JPH0379994(B2) |
申请公布日期 |
1991.12.20 |
| 申请号 |
JP19860143483 |
申请日期 |
1986.06.19 |
| 申请人 |
SENDAI BISEIBUTSU KENKYUSHO |
发明人 |
ITO KUNIHIKO;MAJIMA TOSHIRO;ISHIDA NAKAO;MIZUGAKI MICHINAO |
| 分类号 |
G01N33/53;C12N5/10;C12N15/02;C12P21/08;C12R1/91;G01N33/577 |
主分类号 |
G01N33/53 |
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