发明名称 |
IMMUNOAKTIVE PEPTIDER OG ANTISTOFFER SAMT DERES ANVENDELSE VED ANTI-ALLERGIBEHANDLING |
摘要 |
An immunogen comprising a residue of a histamine-releasing peptide comprising a cationic N-terminal head and a hydrophobic C-terminal tail, together with a residue capable of eliciting antibodies against said peptide whilst inhibiting histamine release by said peptide is useful in anti-allergy treatment. Preferably the histamine-releasing peptide is of formula: Lys-Thr-Lys-Gly-Ser-Gly-Phe-Phe-Val-Phe, optionally amidated at the C terminal. Antibodies to the histamine-releasing peptide are useful for passive immunisation.
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申请公布号 |
NO914937(A) |
申请公布日期 |
1991.12.19 |
申请号 |
NO19910004937 |
申请日期 |
1991.12.13 |
申请人 |
NATIONAL RESEARCH DEVELOPMENT CORPORATION |
发明人 |
STANWORTH, DENIS RAYMOND;LEWIN, IAN VICTOR;NAYYAR, SARITA;JONES, VALERIE |
分类号 |
A61K38/00;A61K39/00;A61K39/35;A61K39/395;A61P37/08;C07K7/06;C07K14/52;C07K16/00;C07K16/06;C07K16/24;C07K16/42;C07K19/00;C12N5/10;C12N15/02;C12P21/08;C12R1/91;(IPC1-7):A61K39/395 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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