COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES

摘要

OF THE DISCLOSURE This invention provides compositions comprising a physiologically-active agent and a compound having the structural formula wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-17 and R is -CH3, or wherein R'' is H or halogen in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.