发明名称 |
INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PATHWAY MEDIATED DISEASES |
摘要 |
2084290 9119497 PCTABS00008 A method of dual inhibition of 5-lipoxygenase pathway mediated diseases and cyclooxygenase pathway mediated diseases in a subject in need thereof which comprises administering to such subject an effective, non-toxic 5-lipoxygenase pathway inhibiting amount or an effective, non-toxic cyclooxygenase pathway inhibiting amount of a diaryl-substituted imidazole fused to a second unsaturated 5 or 6 membered heterocyclic ring containing a nitrogen bridgehead atom wherein said second 5 membered ring also contains a sulfur or oxygen atom or said 6 membered ring may also contain an additional nitrogen atom.
|
申请公布号 |
CA2084290(A1) |
申请公布日期 |
1991.12.13 |
申请号 |
CA19912084290 |
申请日期 |
1991.06.07 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
ADAMS, JERRY L.;BENDER, PAUL E.;GALLAGHER, TIMOTHY F.;HEYS, JOHN R.;PERCHONOCK, CARL;VILLANI, ANTHONY J. |
分类号 |
A61K31/435;A61K31/44;A61K31/445;A61K31/505;A61P43/00;C07D471/04;C07D487/04;C07D498/04;C07D513/04;(IPC1-7):C07D471/04;C07D207/333;C07D233/64 |
主分类号 |
A61K31/435 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|