BICYCLIC CHIRAL COMPOUNDS

摘要

A compound of general formula I(a) and/or I(b) and/or I(c), in which R<1> represents a methyl group or a group of the general formula -CH2.SO2.R<2> or -CH2.SO2.NR<2>R<3>, in which each of R<2> and R<3> independently represents an alkyl, cycloalkyl or optionally substituted phenyl or phenalkyl group; each of R<4>, R<5> and R<6> independently represents a hydrogen atom or a methyl group; X represents a group of formula C(CH3)2 or, when both of R<5> and R<6> represent methyl groups, also represents a group of formula CH2; Q represents an oxygen or sulphur atom; and Y represents a hydrogen atom, an alkali metal atom or a group of the general formula -COA in which A represents a halogen atom or an alkyl or alkoxy group optionally substituted by a phenyl, cycloalkyl, alkoxy or alkylcarbonyl group. The compounds are bicyclic optically active compounds and are useful in the synthesis of optical isomers and separation of optical isomers from mixtures.