Imidazol derivatives, their process for production, intermediates, their application as medicaments and the pharmaceutical compositions containing them.

摘要

The invention relates to the products: in which: A represents a carbocyclic or heterocyclic residue, R represents alkyl, alkenyl, alkynyl, R1, R2, R3 and R4 represent hydrogen; halogen; hydroxyl; cyano; nitro; sulpho; formyl; benzoyl; acyl; acyloxy; carboxyl; mercapto; alkyl; alkenyl; alkynyl; alkoxy; alkylthio; aryl; arylalkyl; arylalkenyl; -(CH2)m-SO2-X-R14; where: either R6 and R7 or R8 and R9 represent hydrogen, alkyl, alkenyl, aryl, arylalkyl, -(CH2)m-SO2-X-R14, either X-R14 represents NH2 or X represents -NH-, -NH-CO-NH- or -NH-CO-, single bond and R14 represents alkyl, alkenyl, aryl, or R6 and R7 or R8 and R9 form a heterocycle with nitrogen, or R8 and R9 represent acyl, alkyl, arylsulphonyl, R5 represents alkylene, Y represents -Y1-B-Y2, where: Y1 represents carbocyclic or heterocyclic aryl, optionally substituted, B represents: either single bond, or -CO-, -NH-CO-, -CO-NH- or -O-(CH2)n-, Y2 represents Y1, if B represents single bond, hydrogen, cyano, carboxyl, and to their salts, to a process for their production and to their application as medicaments.