发明名称 |
METHOD FOR THE SELECTIVE EXTRACORPOREAL PRECIPITATION OF LOW DENSITY LIPOPROTEINS FROM SERUM OR PLASMA |
摘要 |
The method comprises adding to the serum or plasma heparin in a buffer, and precipitating the resulting lipoprotein/heparin complex at the isoelectric point at a pH of 5.05 to 5.25, and subsequently removing it or analyzing the precipitate or the filtrate for diagnostic purposes. A device for extracorporeal precipitation of blood constituents has a container into which blood or blood constituents are fed from a patient via a first pump, and has a filter which is downstream of the container and whose filtrate outlet is connected to a line returning to the patient, where the filter has a second outlet for the precipitate, which outlet is connected to a line returning to the container, where the container is connected via a second pump to the outlet of a first vessel containing a treatment agent, and where the filtrate outlet of the filter is connected to a third pump whose delivery capacity essentially corresponds to the total delivery capacities of the first and second pumps; another method comprises adding to the serum or plasma polyanions in a buffer, and precipitating the resulting lipoprotein/polyanion complex at the isoelectric point at a pH of 5.05 to 5.25, and subsequently removing it or analyzing the precipitate or the filtrate for diagnostic purposes. |
申请公布号 |
EP0174478(B1) |
申请公布日期 |
1991.12.11 |
申请号 |
EP19850109471 |
申请日期 |
1982.09.08 |
申请人 |
B. BRAUN-SSC AG |
发明人 |
SEIDEL, DIETRICH, PROF.;WIELAND, HEINRICH, DR.;RATH, DIETER;ROSSKOPF, GERHARD, DR. |
分类号 |
A61M1/34;A61M1/36;G01N33/92 |
主分类号 |
A61M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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