TRYPANOSOMAL IMMUNOSUPPRESSIVE FACTOR

摘要

The present invention comprises a purified proteinaceous molecule (IL-2R inhibitor) derived from T. cruzi, said proteinaceous molecule having activity as an inhibitor of IL-2R expression. The present invention also comprises a partially purified proteinaceous molecule, compositions of matter containing such proteinaceous molecule and proteinaceous molecules substantially homologous to the T. cruzi derived IL-2R inhibitor. The invention also relates to pharmaceutical compositions and reagents utilizing such IL-2R inhibitors and compositions for immunologic studies.