发明名称 2,3,4,5-TETRAHALOGENOBENZENE DERIVATIVES
摘要 2,3,4,5-trihalogenobenzene derivatives of the formula <IMAGE> in which R is -COOH, -COCl, -COF, -CN, -CONH2, -CH2OH, -CH2Cl, -CHCl2, -CCl3 or -CHO, R1 is H, Cl or F, and R2 is Cl or F, it only being possible for R1 or R2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.
申请公布号 US5072038(A) 申请公布日期 1991.12.10
申请号 US19900459876 申请日期 1990.01.02
申请人 BAYER AKTIENGESELLSCHAFT 发明人 KLAUKE, ERICH;PETERSEN, UWE;GROHE, KLAUS
分类号 A61K31/47;A61K31/495;A61K31/535;A61P31/04;C07B31/00;C07B39/00;C07C17/00;C07C17/14;C07C17/16;C07C17/18;C07C17/20;C07C25/13;C07C27/00;C07C33/46;C07C45/00;C07C45/29;C07C45/43;C07C47/24;C07C47/55;C07C51/00;C07C53/50;C07C63/70;C07C67/00;C07C233/00;C07C233/65;C07C253/00;C07C255/49;C07C255/50;C07D215/56;C07D401/04;C07D413/04 主分类号 A61K31/47
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