REMOVAL OF SUBSTANCE ORIGINATED FROM ESCHERICHIA COLI

摘要

PURPOSE:To efficiently remove substances originated from Escherichia coli from the aqueous solution of genetic recombination proteins prepared with the Escherichia coli, by bringing an aqueous solution containing the substances into contact with a non-polar porous polymer resin to adsorb the substances on the resin. CONSTITUTION:An aqueous solution containing substances originated from Escherichia coli is brought into contact with a non-polar high porous polymer to adsorb the substances on the resin. The substances include typically cell body proteins and pyrogenic substances and the method is remarkable on the point that both the substances are simultaneously removed. The aqueous solution containing the substances originated from the Escherichia coli is usually an aqueous solution containing proteins prepared by genetic recombination methods using the Escherichia coli as a host.